2026-10-22
Max Kozlov
Analysis of nearly 30,000 brain scans yields detailed timeline of how the brain matures — and hints at the consequences of disrupting it.
DOI: 10.1038/d41586-026-03357-92026-10-22
Anil Kumar Singh, León Martin, Matea Sršen, Freja Schou Guttesen, Bing-Zhong Hu, Yuta Ito, Stephan Korsgaard Pedersen, Fadhil Suleiman Kamounah, Fabian Pauly, Michael Pittelkow, Jing-Tao Lü, Per Hedegård, Oren Tal
DOI: 10.1038/s41586-026-11312-x2026-10-22
Shamini Bundell
From underwater speakers to growing super-corals, scientists battle to save reefs around the world.
DOI: 10.1038/d41586-026-03414-32026-10-22
Heidi Ledford
Application of the high-precision technique is part of a clinical trial to treat a genetic disease that can cause liver and nerve damage.
DOI: 10.1038/d41586-026-03371-x2026-10-22
Terence Tao
As machines race ahead in solving problems, mathematicians must establish a new era that prizes human understanding over simply publishing more solutions.
DOI: 10.1038/d41586-026-03389-12026-10-21
Junsung Woo, Michael R. Williamson, Dongjoo Choi, Ekin Akdemir, Thea Zlatkov, Kwanha Yu, Wookbong Kwon, Ehson Maleki, Yeunjung Ko, Kaitlyn Sanchez, Hussein Maleki, Jong Min Choi, Akdes Serin-Harmanci, Benjamin Deneen
CD51+ astrocytes promote synapse formation in the developing cortex, circuit plasticity in the hippocampus and circuit remodelling after stroke.
DOI: 10.1038/s41586-026-11186-z2026-10-21
Fabrizio Sergio, Haruki Natsukawa, Alessandro Tanferna, Javier Chicano, Francisco Carro, Ramón C. Soriguer, Fernando Hiraldo, Julio Blas
Climate-driven drought and prey decline triggered lynx predation on raptors, reducing raptor fitness and abundance and producing cascading effects across lower trophic levels.
DOI: 10.1038/s41586-026-11194-z2026-10-21
Hanseul Lee, Seung-Jae V. Lee
In nematodes, a metabolite induced by the cold links low temperatures to a body-wide signal that promotes longevity. This signalling system is also seen in human cells.
DOI: 10.1038/d41586-026-03066-32026-10-21
Hyun Ju Lee, Cansu Doğan, Seda Koyuncu, Markus Wehrmann, Murat Artan, Dunja Petrovic, Rute Loureiro, Amit Kumar Sahu, Joana Schnubel, Pavel Grobushkin, Dimitrios Prymidis, Theodoros Georgomanolis, Agnieszka Sokol, Ming Yang, Thorsten Hoppe, Christian Frezza, David Vilchez
A multi-tissue signalling system links cold temperature to enhanced longevity and proteostasis in Caenorhabditis elegans.
DOI: 10.1038/s41586-026-11152-92026-10-21
Shanshan Yao
Touch-sensitive, light-emitting yarn can turn everyday clothing into washable, bendable user interfaces with dynamic graphics and versatile computing functions.
DOI: 10.1038/d41586-026-03064-52026-10-21
Changmeng Liu, Yinan Cui, Jiachen Wang, Xiao Han, Zhongao Ji, Zhun Liang, Chongle Zhang, Jaime Marian, Zixiang Li, Tao Lu, Tianqiu Xu, Jinyu Zhang, Wei Cui, Wei Liu, Daining Fang, Y. Morris Wang
A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single crystals of Ti-6Al-4V, as well as hard-to-process refractory metals, including W, Mo, Nb and MoNb alloys.
DOI: 10.1038/s41586-026-11185-02026-10-21
Rusty A. Feagin, M. Luisa Martínez
Salt-marsh plants can protect inland areas against huge waves — but seemingly only up to a point, and big storms cause progressive damage.
DOI: 10.1038/d41586-026-03063-62026-10-21
Ruiliang Gao, Liwei Zhang, Richard J. Lewis, Hao Wang, Zhiyan Pan, Yage Zhang, Zekai Yu, Zhiqiang Liu, Xiaolin Guo, Xiangbowen Du, Wencong Liu, Minghang Li, Shipan Liang, Bing Lu, Ichiro Daigo, Shanjun Mao, Graham J. Hutchings, Yong Wang
DOI: 10.1038/s41586-026-11252-62026-10-21
Gregory S. Rohrer
A 3D-printing method has made single crystals of metals and alloys in complex shapes and up to one metre in length, as needed for advanced technological applications.
DOI: 10.1038/d41586-026-03257-y2026-10-21
Fengyuan Dai, Shiyang You, Yudian Zhu, Yuan Gao, Lihao Fu, Xibin Zhou, Jin Su, Chentong Wang, Yuliang Fan, Qingsong Tan, Xiaoxiao Ma, Xianjun Deng, Letong Yu, Hui Qian, Yan He, Yitao Ke, Zhe Zhang, Chenchen Han, Xing Chang, Liangzhen Zheng, Sheng Wang, Yuan Ji, Kexin Hao, Longxing Cao, Yajie Wang, Anping Zeng, Shunzhi Wang, Chunjun Zhan, Jing Zhao, Tong Si, Jianming Liu, Hongyuan Lu, Fajie Yuan
Pinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation product yields without iterative optimization.
DOI: 10.1038/s41586-026-11205-z2026-10-21
An innovative artificial-intelligence application enhances weather forecasting in the difficult subseasonal range, providing accurate forecasts of precipitation, temperature and pressure 3–5 weeks in advance. The tool refines both physics- and AI-based weather models and improves the early prediction of extremes of heat, cold, rainfall and flooding.
DOI: 10.1038/d41586-026-03077-02026-10-21
Heidi Ledford
Money from the world’s increasingly prosperous technology entrepreneurs has been flooding into biomedical research. Is it changing how science is done?
DOI: 10.1038/d41586-026-03311-92026-10-21
Embedding enzymes that break down ester bonds into compostable polyesters enables rapid and complete biodegradation even in microbe-scarce environments. This method is effective in marine sites ranging from coastal sea water to the deep sea, and could therefore contribute towards solving the global plastic pollution problem.
DOI: 10.1038/d41586-026-03282-x2026-10-21
James Dinneen
The United Nations’ latest climate report is a stark reminder that limiting warming to the safest levels is now likely out of reach.
DOI: 10.1038/d41586-026-03355-x2026-10-21
Analysis of some nearby stars shows that, despite their name, these bodies can be pink, yellow and more.
DOI: 10.1038/d41586-026-03319-12026-10-21
Benjamin Thompson
Experiment shows how these ecosystems could protect coastlines from huge storms — plus, new evidence hints at what Denisovans might have looked like.
DOI: 10.1038/d41586-026-03376-62026-10-21
Kay E. Davies
Researcher and policy adviser who championed tests and treatments for genetic diseases.
DOI: 10.1038/d41586-026-03375-72026-10-21
Song Xing, Zhongyou Wu, Qingfeng Shao, Junyi Ge, E. Andrew Bennett, Huiyun Rao, Sungui Lin, Yuhao Zhao, Feng Liu, Yichen Liu, Kai Zhou, Xiaotian Feng, Qigao Jiangzuo, Qiaomei Fu
Denisovans from the Xujiayao and other East Asian sites are morphologically distinctive, with a low cranial profile with near-parallel lateral walls, a massive supraorbital torus, a flat zygomaxillary region and weak prognathism.
DOI: 10.1038/s41586-026-11132-z2026-10-21
Yue Yi, Zuorong Cao, Kejia Wu, Hengwu Ding, Lin Fu, Wenyi Gao, Ling Li, Lei Zhou, Zhuo Zhou, Lirong Dai, Yahai Lu, Lei Cheng
Methanoglobus dolicholipophagus AA-75 is a thermophilic archaeon isolated from a Chinese petroleum reservoir that converts methanol into methane, carbon dioxide and acetate, and uses saturated and unsaturated fatty acids to produce methane.
DOI: 10.1038/s41586-026-11207-x2026-10-21
Luciana V. Gatti, Camilla L. Cunha, Juan C. G. Blas, A. Scott Denning, Mariane S. Reis, Luciano Marani, Egidio Arai, Cassiano Gustavo Messias, Dhemerson E. Conciani, John B. Miller, Vanúcia Schumacher, Kleber P. Naccarato, Jose Marengo, Ane A. C. Alencar, Luciana Soler, Claudio Almeida, Lucas Gatti Domingues, Caio S. C. Correia, Raiane A. L. Neves, Carlos Nobre, Sergio M. Corrêa, Elliott Campbell, Jennifer E. Johnson, Joseph A. Berry, Alber H. Sanchez, Francine M. da Silva, Vagner L. Camilotti, Christiane Silvestrini, Filipe Loyola Lopes, Xin Lan, Gabrielle Pétron, Marcio Malacarne, Guilherme B. M. Machado
Fifteen years of atmospheric CO2 measurements show that the Amazon carbon sink is weakening, with fires, deforestation and climate stress driving increasingly high carbon emissions.
DOI: 10.1038/s41586-026-11168-12026-10-21
Luc-Alban Vuillemenot, Lucas G. Morales, Calin-Mihai Dragoi, Betheney R. Pennycook, Edward Harris, Liuyang C. Lin, William A. Weston, Jade-Ellen Brown, Emma Graham, Leelou Moulin, Ivan Andrew, Georgia Roumelioti, Alex Montoya, Laurence Game, George R. Young, Keshava K. Datta, Pavel Shliaha, Béla Novák, Hiroyuki Yamano, Alexis R. Barr
Experimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the toxic side effects of WEE1 inhibitors in cancer therapies.
DOI: 10.1038/s41586-026-11188-x2026-10-21
QiuYuan Huang, Noriko Iida, Noriyuki Isobe, Taizo Kabe, Taku Omura, Manikandan Ilangovan, Satoshi Kimura, Jin Ho Seok, Hidetaka Nomaki, Ken-ichi Kasuya, Tadahisa Iwata
Near-complete deep-sea degradation of enzyme-embedded compostable polyesters shows that thermal enzyme embedding greatly accelerates breakdown across marine environments while preserving material performance, offering a promising strategy to mitigate persistent ocean plastic pollution.
DOI: 10.1038/s41586-026-11192-12026-10-21
Sandip Mishra, Payal, Declan Evans, Kingsley Bortey, Husayn Bootwala, Giovanni Gonzalez-Gutierrez, Ricardo Javier Vázquez, David Baker, Jared C. Lewis
DOI: 10.1038/s41586-026-11317-62026-10-21
Sarah Wild
Tolullah Oni has developed a platform to transfer the intellectual capital of African diaspora scholars back to the continent.
DOI: 10.1038/d41586-026-03161-52026-10-21
Heng Fu, Ziang Li, Swetika Chaturvedi, Xiaoyu Zhang, Xiaolong Li, Qianyi Li, Tural Khudiyev
Multifunctional digital fibres integrate display, touch sensing, computation and multimodal input–output, enabling flexible, washable garments with interactive graphical interfaces and wireless multimedia capabilities.
DOI: 10.1038/s41586-026-11128-9