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NATURE

Publisher:
Springer Nature
ISSN:
2698-6248
Category:
MULTIDISCIPLINARY SCIENCES
Impact factor:
50.5

Feed status

655 parsed articles

Last update: 2026-10-23

Latest articles

Cold activates a BH2 metabolic network promoting longevity and proteostasis

2026-10-21

Hyun Ju Lee, Cansu Doğan, Seda Koyuncu, Markus Wehrmann, Murat Artan, Dunja Petrovic, Rute Loureiro, Amit Kumar Sahu, Joana Schnubel, Pavel Grobushkin, Dimitrios Prymidis, Theodoros Georgomanolis, Agnieszka Sokol, Ming Yang, Thorsten Hoppe, Christian Frezza, David Vilchez

A multi-tissue signalling system links cold temperature to enhanced longevity and proteostasis in Caenorhabditis elegans.

DOI: 10.1038/s41586-026-11152-9

Additive manufacturing of ultralong and architected single crystals

2026-10-21

Changmeng Liu, Yinan Cui, Jiachen Wang, Xiao Han, Zhongao Ji, Zhun Liang, Chongle Zhang, Jaime Marian, Zixiang Li, Tao Lu, Tianqiu Xu, Jinyu Zhang, Wei Cui, Wei Liu, Daining Fang, Y. Morris Wang

A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single crystals of Ti-6Al-4V, as well as hard-to-process refractory metals, including W, Mo, Nb and MoNb alloys.

DOI: 10.1038/s41586-026-11185-0

Programmable design of functional proteins from natural language

2026-10-21

Fengyuan Dai, Shiyang You, Yudian Zhu, Yuan Gao, Lihao Fu, Xibin Zhou, Jin Su, Chentong Wang, Yuliang Fan, Qingsong Tan, Xiaoxiao Ma, Xianjun Deng, Letong Yu, Hui Qian, Yan He, Yitao Ke, Zhe Zhang, Chenchen Han, Xing Chang, Liangzhen Zheng, Sheng Wang, Yuan Ji, Kexin Hao, Longxing Cao, Yajie Wang, Anping Zeng, Shunzhi Wang, Chunjun Zhan, Jing Zhao, Tong Si, Jianming Liu, Hongyuan Lu, Fajie Yuan

Pinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation product yields without iterative optimization.

DOI: 10.1038/s41586-026-11205-z

An AI tool improves weather forecasts up to a month ahead

2026-10-21

An innovative artificial-intelligence application enhances weather forecasting in the difficult subseasonal range, providing accurate forecasts of precipitation, temperature and pressure 3–5 weeks in advance. The tool refines both physics- and AI-based weather models and improves the early prediction of extremes of heat, cold, rainfall and flooding.

DOI: 10.1038/d41586-026-03077-0

The proteome of Middle Pleistocene Xujiayao and common Denisovan morphology

2026-10-21

Song Xing, Zhongyou Wu, Qingfeng Shao, Junyi Ge, E. Andrew Bennett, Huiyun Rao, Sungui Lin, Yuhao Zhao, Feng Liu, Yichen Liu, Kai Zhou, Xiaotian Feng, Qigao Jiangzuo, Qiaomei Fu

Denisovans from the Xujiayao and other East Asian sites are morphologically distinctive, with a low cranial profile with near-parallel lateral walls, a massive supraorbital torus, a flat zygomaxillary region and weak prognathism.

DOI: 10.1038/s41586-026-11132-z

Amazon carbon emissions driven by human actions amplified by droughts

2026-10-21

Luciana V. Gatti, Camilla L. Cunha, Juan C. G. Blas, A. Scott Denning, Mariane S. Reis, Luciano Marani, Egidio Arai, Cassiano Gustavo Messias, Dhemerson E. Conciani, John B. Miller, Vanúcia Schumacher, Kleber P. Naccarato, Jose Marengo, Ane A. C. Alencar, Luciana Soler, Claudio Almeida, Lucas Gatti Domingues, Caio S. C. Correia, Raiane A. L. Neves, Carlos Nobre, Sergio M. Corrêa, Elliott Campbell, Jennifer E. Johnson, Joseph A. Berry, Alber H. Sanchez, Francine M. da Silva, Vagner L. Camilotti, Christiane Silvestrini, Filipe Loyola Lopes, Xin Lan, Gabrielle Pétron, Marcio Malacarne, Guilherme B. M. Machado

Fifteen years of atmospheric CO2 measurements show that the Amazon carbon sink is weakening, with fires, deforestation and climate stress driving increasingly high carbon emissions.

DOI: 10.1038/s41586-026-11168-1

WEE1 opposes APC/C CDH1 activity to promote S phase entry

2026-10-21

Luc-Alban Vuillemenot, Lucas G. Morales, Calin-Mihai Dragoi, Betheney R. Pennycook, Edward Harris, Liuyang C. Lin, William A. Weston, Jade-Ellen Brown, Emma Graham, Leelou Moulin, Ivan Andrew, Georgia Roumelioti, Alex Montoya, Laurence Game, George R. Young, Keshava K. Datta, Pavel Shliaha, Béla Novák, Hiroyuki Yamano, Alexis R. Barr

Experimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the toxic side effects of WEE1 inhibitors in cancer therapies.

DOI: 10.1038/s41586-026-11188-x

Enzyme-embedded polyesters for accelerated biodegradation in the deep sea

2026-10-21

QiuYuan Huang, Noriko Iida, Noriyuki Isobe, Taizo Kabe, Taku Omura, Manikandan Ilangovan, Satoshi Kimura, Jin Ho Seok, Hidetaka Nomaki, Ken-ichi Kasuya, Tadahisa Iwata

Near-complete deep-sea degradation of enzyme-embedded compostable polyesters shows that thermal enzyme embedding greatly accelerates breakdown across marine environments while preserving material performance, offering a promising strategy to mitigate persistent ocean plastic pollution.

DOI: 10.1038/s41586-026-11192-1