2026-04-01
Khanh T. Nguyen, O. Sila Ozgur, Rohil Jain, Christopher Taveras, Emmanuella O. Ajenu, Tyler Pugeda, Alona Muzikansky, Seyed Alireza Rabi, Asishana A. Osho, John N. Kheir, Daryoosh Vakhshoori, Korkut Uygun, Padraic Romfh, Shannon N. Tessier
Communications Medicine, Published online: 01 April 2026; doi:10.1038/s43856-026-01551-4 Nguyen, Ozgur et al. applied resonance Raman Spectroscopy (RRS) to monitor mitochondrial redox states in rat and pig livers during reperfusion after warm ischemia, including resolving redox changes at complexes III and IV. RRS detects early mitochondrial hyperoxidation, particularly at complex III and that RRS guided treatment with methylene blue can restore function in injured livers, highlighting its potential for improving organ assessment and rescue in transplantation.
2026-04-01
Hanan Abumanhal-Masarweh, Salam A. Assi, Xinming Liu, Conrado Guerrero Quiles, Taha Lodhi, Kaye J. Williams, Eleanor J. Cheadle, Kostas Kostarelos, Ananya Choudhury, David C. Wedge, Catharine M. L. West, Marilena Hadjidemetriou
Communications Medicine, Published online: 01 April 2026; doi:10.1038/s43856-026-01552-3 Abumanhal-Masarweh et al. profile plasma proteomes of cancer patients during radiotherapy and detect acute changes in inflammatory and immune pathways. Correlating these changes with toxicity data enables identification of a predictive signature for radiation-induced toxicities.
2026-04-01
Mats Ingmar Fortmann, Rebecca Dappen, Claudia Roll, Margarita Kozhuharova, Axel von der Wense, Christoph Härtel, Julia Sandkötter, Egbert Herting, Wolfgang Göpel, Alexander Humberg
Communications Medicine, Published online: 01 April 2026; doi:10.1038/s43856-026-01569-8 Fortmann and Dappen et al., investigate whether repeated neonatal elevations of C-reactive protein predict long-term lung health in very preterm infants. They report that recurrent inflammation correlates with poorer lung function and reduced exercise capacity at school age, underscoring its lasting impact on respiratory development.
2026-03-31
Shunsuke Hamada, Miharu Suda, Katsuyasu Ishida, Kei Furihata, Yoshitaka Sogawa, Masafumi Kumazaki, Kaori Takahashi, Sachiko Sakakibara, Satoko Matsunaga, Nao Jonai, Tetsuo Nakayama, Fumihiko Takeshita
Communications Medicine, Published online: 31 March 2026; doi:10.1038/s43856-025-01215-9 Hamada et al., evaluated the efficacy, immunogenicity and safety of monovalent and bivalent lipid nanoparticle-mRNA vaccine, DS-5670, against SARS-CoV-2 variants in two randomized trials. Findings show DS-5670 is as effective as existing mRNA vaccines, with broad neutralization activity across omicron sub-lineages.