ANP produced from self-amplifying RNA improves cardiac function after MI
2026-03-24
Gregory B. Lim
Nature Reviews Cardiology, Published online: 24 March 2026; doi:10.1038/s41569-026-01282-y In a new study, treatment with self-amplifying RNA contained in lipid nanoparticles to increase the production of atrial natriuretic peptide preserved ventricular function and reduced cardiac fibrosis in mouse and pig models of myocardial infarction.