2026-09-16
Stephen M. Fleming
The capacity to self-evaluate and control one’s own cognitive performance, known as metacognition, underpins adaptive learning, social behaviours and self-belief. Stephen Fleming outlines our current understanding of the neural basis of metacognition, its contributions to self-regulation and social communication, and the consequences of its dysfunction in clinical conditions.
DOI: 10.1038/s41583-026-01081-x2026-09-14
Yu Qi
In this Journal Club, Yu Qi discusses a 2021 study that reported a brain–computer interface that used neural activity in the motor cortex to decode attempted handwriting in real time.
DOI: 10.1038/s41583-026-01082-w2026-09-11
Jeremy S. Biane, Julian Wagner-Carena, Mazen A. Kheirbek
Recent years have witnessed major advances in our understanding of the distinct functional and computational roles of the ventral hippocampus (vHPC). Mazen Kheirbek and colleagues examine the state-dependent representation of behaviourally salient information by the vHPC and discuss how its anatomy and circuit connectivity support affective and motivational behaviours.
DOI: 10.1038/s41583-026-01078-62026-09-11
Alberto E. Pereda, Adam C. Miller
The mechanisms underlying electrical transmission are often viewed as relatively simple compared with those mediating chemical transmission, yet electrical synapses exhibit dynamic changes in structure and strength. In this Review, Alberto Pereda and Adam Miller examine the structural and molecular bases and complexities of electrical transmission.
DOI: 10.1038/s41583-026-01080-y2026-08-28
Darran Yates
A new study reports that olfactory receptor genes in the mosquito Aedes aegypti can be coexpressed in olfactory neurons and expressed in multiple subtypes of these neurons.
DOI: 10.1038/s41583-026-01077-72026-08-28
Tal Golan, Heiko H. Schütt, Nikolaus Kriegeskorte
Neural network models can express computational hypotheses about brain information processing, but their high parametric capacity makes discriminating model alignment to experimental data challenging. In this Review, Kriegeskorte and colleagues discuss methodology for the optimization of stimuli that make models disagree in their predictions of neural and behavioural data and enhance model comparison.
DOI: 10.1038/s41583-026-01070-02026-08-27
Jake Rogers
Humans learn the extent to which outcomes are causally attributable to performance through dorsomedial prefrontal cortex tracking decision confidence to estimate the level of control in an environment as well as controllability changes via its interactions with the dorsal raphe nucleus.
DOI: 10.1038/s41583-026-01076-82026-08-27
Sian Lewis
Injury to hand nerves can lead to disordered digit representation, which is now shown to arise as a result of altered peripheral inputs following nerve regeneration.
DOI: 10.1038/s41583-026-01079-5