Acta Brasiliensis

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ISSN:: 2526-432X
Category:: AGRICULTURE, MULTIDISCIPLINARY
Impact factor:: 0.2

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In vitro evaluation of the antioxidant potential of derivatives eugenol via ABTS radical capture assay

2023-12-30

Josefa Aqueline Cunha Lima, Jadson de Farias Silva, Macilio Martins de Moraes, Carolina Alves de Araujo, Claudio Augusto Gomes da Câmara, Juliano Carlo Rufino Freitas

Eugenol is a natural product present in different plant species, especially in the flower buds of Syzygiu Aromatum . This secondary metabolite exhibits antioxidant action, in addition to acting as an anti-inflammatory, antitumor, antibacterial, antifungal, antipyretic, anesthetic and analgesic agent. Given the biological potential of eugenol, the antioxidant activity of eugenol derivatives was evaluated. Thus, eugenol isolated from flower buds of Syzygiu aromaticum was subjected to different types of reactions such as O -alkylation. The eugenol derivatives were characterized by 1 H and 13 C NMR techniques. The evaluation of antioxidante activity was carried out using the ABTS radical capture assay. Six derivatives were synthesized with yields ranging from 75-92%, which exhibited low antioxidant potential compared to radical capture assays, with EC 50 values from 0.085 to 0.327 mg/mL. These results motivate new studies, since the search for new antioxidant agents is extremely necessary in view of the numerous pathologies that are associated with oxidative stress.

Monogeneans of Prochilodus nigricans (Prochilodontidae) in southwestern Amazonia

2023-12-30

Ronaldo Alves Silva, Henrique Melo, Ricardo Massato Takemoto, Dionatas Meneguetti, Lucena Rocha Virgilio

Monogenoids are mostly ectoparasites known for their infestations in fish farming environments and found in fish gills. The fauna of monogeneans of Prochilodus nigricans , whether in natural or artificial environments, have been reported. However, few studies have addressed the study of the community and distribution of the fauna of these ectoparasites. In this sense, the objective of the present study was to evaluate the community, occurrence, and distribution of the fauna of monogeneans of P. nigricans in rivers of the western Amazon. Specimens were collected in four different rivers in the southwest of the Amazon. In the laboratory, fish gills were removed and sorted, and the ectoparasites were collected. Monogenea species found were mounted on slides and identified. There was a low abundance of monogeneans in P. nigricans in the region and a high species richness of these parasites, and their species composition varied between river environments. In addition, the present study represents the first record of Anacanthoroides mizellei and Curvianchoratus sp. in P. nigricans and Tereancistrum curimba in the western Amazon. Information regarding the distribution and occurrence of monogeneans in fish is interesting, as it can contribute to global estimates of the distribution of these parasites in fish.