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ANALYST

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ISSN:
0003-2654
Category:
CHEMISTRY, ANALYTICAL
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40 parsed articles

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Latest articles

Lyophilised colourimetric LAMP for visual readout with dual colour indicators

2026-03-26

Kenny Malpartida-Cardenas, Oliver W. Stringer, Matthew L. Cavuto, Alison Holmes, Jesus Rodriguez-Manzano

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01238D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Kenny Malpartida-Cardenas, Oliver W. Stringer, Matthew L. Cavuto, Alison Holmes, Jesus Rodriguez-Manzano Development and optimisation of ready-to-use lyophilised colourimetric LAMP (lyo-cLAMP) integrating pH and metal indicators, only requiring addition of extracted nucleic acids. Compatible with any LAMP assay, it enables adaptation to any target. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Environmentally Benign Synthesis of Blue Fluorescent Graphene Quantum Dots for Nitroaromatic Sensing (p-Nitroaniline and 2,4,6-Trinitrophenol) and Nanophytotoxicity Analysis

2026-03-26

Krishna Moni Deka, Saikat Das, Rachita Newar, Rajkanya Das, Bappy Sen, Hemen Sarma, Arabinda Baruah

Analyst , 2026, Accepted Manuscript DOI : 10.1039/D6AN00045B, Paper Krishna Moni Deka, Saikat Das, Rachita Newar, Rajkanya Das, Bappy Sen, Hemen Sarma, Arabinda Baruah This work introduces an environmentally benign route for producing strongly blue-emissive graphene quantum dots (GQDs) from graphene oxide synthesized via a modified Tour method. GQDs are nanoscale (<10 nm) fragments... The content of this RSS Feed (c) The Royal Society of Chemistry

Thiol-Phenolic Interactions in Electropolymerized Methimazole Enable Superior Isomer Discrimination for Hydroquinone and Catechol Sensing

2026-03-25

Dexian Kong, Jiajin Feng, Shiting Deng, Mingwei Yang, Yuwu Chi

Analyst , 2026, Accepted Manuscript DOI : 10.1039/D6AN00061D, Paper Dexian Kong, Jiajin Feng, Shiting Deng, Mingwei Yang, Yuwu Chi A new electropolymerized methimazole (p-MMI) film-modified glassy carbon electrode was developed for simultaneous detection of hydroquinone (HQ) and catechol (CC). The p-MMI/GCE was fabricated through cyclic voltammetric deposition of methimazole,... The content of this RSS Feed (c) The Royal Society of Chemistry

Portable and point-of-care molecular detection of pathogenic Vibrio parahaemolyticus in shrimp

2026-03-24

Thi Ngoc Diep Trinh, Kieu The Loan Trinh, Hanh An Nguyen, Huynh Minh Triet Nguyen, Nguyen Thi Hong Nhi, Vo Thi Tuyet Minh, Nguyen Nhat Nam, Nae Yoon Lee

Analyst , 2026, Accepted Manuscript DOI : 10.1039/D6AN00099A, Paper Thi Ngoc Diep Trinh, Kieu The Loan Trinh, Hanh An Nguyen, Huynh Minh Triet Nguyen, Nguyen Thi Hong Nhi, Vo Thi Tuyet Minh, Nguyen Nhat Nam, Nae Yoon Lee In the Mekong Delta regions, Acute Hepatopancreatic Necrosis Disease (AHPND) is a globally serious threat for shrimp farming. AHPND is mainly caused by Vibrio parahaemolyticus carrying the plasmid that encodes... The content of this RSS Feed (c) The Royal Society of Chemistry

Ultra-sensitive photoelectrochemical aptasensor based on a CdIn2S4/ZnSnO3 composite for the detection of adenosine triphosphate

2026-03-24

Ling Zhang, Lu-Ying Wang, Yu-Ping Wei, Jingshuai Chen, Hui Zhu, Xing-Pei Liu, Chang-Jie Mao, Bao-Kang Jin

Analyst , 2026, Accepted Manuscript DOI : 10.1039/D6AN00158K, Paper Ling Zhang, Lu-Ying Wang, Yu-Ping Wei, Jingshuai Chen, Hui Zhu, Xing-Pei Liu, Chang-Jie Mao, Bao-Kang Jin Adenosine triphosphate (ATP) is an important extracellular signaling molecule in the human body. Its abnormal expression is closely related to the occurrence and development of various diseases, and accurate detection... The content of this RSS Feed (c) The Royal Society of Chemistry

A hollow-core fiber based optofluidic chip for rapid immunofluorescence detection with simultaneous enhancement of sensitivity and enrichment efficiency

2026-03-23

Xiao Ren, Tian Wen, Yukai Liu, Xiaoxian Liu, Feng Lin, Zhenyong Dong, Hao Wang, Lunbiao Cui, Yan-qing Lu, Guanghui Wang

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01308A, Paper Xiao Ren, Tian Wen, Yukai Liu, Xiaoxian Liu, Feng Lin, Zhenyong Dong, Hao Wang, Lunbiao Cui, Yan-qing Lu, Guanghui Wang An optical microfluidic chip integrating a functionalized hollow-core fiber achieves rapid and highly sensitive detection of influenza A virus through waveguide-confined fluorescence excitation enhancement and efficient collection. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Glycan signal enhancement by ammonium fluoride doping and electrospray diverting

2026-03-23

Seth M. Eisenberg, David C. Muddiman

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00090H, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Seth M. Eisenberg, David C. Muddiman By combining ammonium fluoride electrospray doping with an electrospray diverter, signals of N -linked glycans were significantly enhanced. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Stable focusing of proteins within a packed microbead bed by ion concentration polarization in a paper-based analytical device

2026-03-23

Sommer Osman, Kira L. Rahn, Quinlan G. Pollak, Md Ruhul Amin, Robbyn K. Anand

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00004E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Sommer Osman, Kira L. Rahn, Quinlan G. Pollak, Md Ruhul Amin, Robbyn K. Anand Embedded beads stabilize electrokinetic preconcentration in a paper LFA, while antibody functionalization enables antigen retention after the electric field is removed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

A spatially invariant noise model for minimum noise fraction (MNF) denoising of hyperspectral datasets: applications to large-scale infrared spectroscopic pathology

2026-03-20

Dougal Ferguson, Peter Gardner

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00152A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Dougal Ferguson, Peter Gardner A spatially invariant version of the Minimum Noise Fraction denoising algorithm (iMNF) that removes the spatial-order dependency of standard MNF, keeping biochemical fidelity across unstructured datasets or datasets analysed in a patch-wise manner*. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

High- and low-field NMR in binary solvent gradients

2026-03-20

Haider Hussain, Paulina Putko, Dariusz Gołowicz, Krzysztof Kazimierczuk, Matthew Wallace

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00031B, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Haider Hussain, Paulina Putko, Dariusz Gołowicz, Krzysztof Kazimierczuk, Matthew Wallace Gradients in the solvent composition of NMR samples are generated by layering two solvents of contrasting densities. Spectra are recorded at different compositions by physical movement of the tube (low-field) or chemical shift imaging (high-field). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Simultaneous qualitative and quantitative analysis of tyloxapol in tobramycin eye drops by LC-Q-TOF and HPLC-ELSD

2026-03-18

Shengjun Che, Chen Liang, Min Yan, Xiaoru Zhang, Wenfeng Zheng

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00042H, Paper Shengjun Che, Chen Liang, Min Yan, Xiaoru Zhang, Wenfeng Zheng An innovative combined qualitative and quantitative method for detecting the content of tyloxapol in tobramycin eye drops. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Machine Learning-Driven Multidimensional Tea Profiling from a Single SERS Spectrum: Toward Practical Application

2026-03-18

Jincheng Ni, Yanyan Lu, Xuewen Chen, Haoming Bao, Yu Qiao, Shuai Zhang, Daoshuan Ding, Jiamei Jin, Huaiyuan Zhao, Qian Zhao, Jinhua Wang, Hongwen Zhang, Weiping Cai

Analyst , 2026, Accepted Manuscript DOI : 10.1039/D6AN00093B, Paper Jincheng Ni, Yanyan Lu, Xuewen Chen, Haoming Bao, Yu Qiao, Shuai Zhang, Daoshuan Ding, Jiamei Jin, Huaiyuan Zhao, Qian Zhao, Jinhua Wang, Hongwen Zhang, Weiping Cai Multidimensional tea profiling is crucial for both consumer experience, brand reputation, and market integrity. Here, we introduce a rapid and systematic strategy for multidimensional tea authentication based on a single... The content of this RSS Feed (c) The Royal Society of Chemistry

Micro-SORS and machine learning for the non-invasive reference-free study of subsurface pigment degradation

2026-03-17

A. Lux, J. Schlanz, A. Botteon, L. Monico, P. Matousek, R. I. Dima, C. Conti, P. Strobbia

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01176K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. A. Lux, J. Schlanz, A. Botteon, L. Monico, P. Matousek, R. I. Dima, C. Conti, P. Strobbia The study presents the development of micro-spatially offset Raman spectroscopy (micro-SORS) methods and data analysis routines for the study of pigment degradation processes in the cultural heritage field. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Classification of recycled plastics using sparse and imbalanced spectral data and data augmentation by the generative adversarial network

2026-03-17

Xuan Liu, Xuerui Song, Yusuf Sulub, David Zoller, Zhenyu (James) Kong, Blake N. Johnson

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01042J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Xuan Liu, Xuerui Song, Yusuf Sulub, David Zoller, Zhenyu (James) Kong, Blake N. Johnson Data augmentation with a Generative Adversarial Network improves FTIR spectra classification for accurate plastic sorting and recycling applications. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Utilizing Venturi effect for automated high-throughput droplet-MS from well plates

2026-03-16

Bridget E. Murray, Roger C. Diehl, Moritz Pott, Daniel A. Holland-Moritz, Alison R. H. Narayan, Robert T. Kennedy

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00065G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Bridget E. Murray, Roger C. Diehl, Moritz Pott, Daniel A. Holland-Moritz, Alison R. H. Narayan, Robert T. Kennedy We demonstrate a high-throughput (0.4 samples per s) and automated droplet-MS method for analysis of enzyme reactions. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Multimodal AFM-IR nanospectroscopy and non-linear optical microscopy for detecting collagen matrix alterations

2026-03-09

Jérémie Mathurin, Gaël Latour, Gervaise Mosser, Alexandre Dazzi, Marie-Claire Schanne-Klein, Ariane Deniset-Besseau

Analyst , 2026, 151 ,1881-1888 DOI : 10.1039/D5AN01298H, Communication Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Jérémie Mathurin, Gaël Latour, Gervaise Mosser, Alexandre Dazzi, Marie-Claire Schanne-Klein, Ariane Deniset-Besseau Correlative photothermal IR nanospectroscopy (AFM-IR) and non-linear optical microscopy analyses reveal that the emergence of a 1730 cm −1 band in collagen arises from local, thermally induced chemical alteration. The content of this RSS Feed (c) The Royal Society of Chemistry

Juniper-based Cu@activated carbon functionalized with ethylenediamine: a green platform for non-enzymatic detection of dopamine

2026-03-03

Afef Dhaffouli, Pedro A. Salazar-Carballo, Soledad Carinelli, Lívia Flório Sgobbi, Adam Slabon, Bruno V. M. Rodrigues

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01141H, Paper Afef Dhaffouli, Pedro A. Salazar-Carballo, Soledad Carinelli, Lívia Flório Sgobbi, Adam Slabon, Bruno V. M. Rodrigues A green sensor based on juniper seed activated carbon functionalized with Cu-NPs and amine groups enables nanomolar dopamine detection. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Lighting up hypochlorous acid through C(sp2)–H hydroxylation with a solvatochromic organoiridium(III) complex-based probe

2026-03-02

Bhaskar Sen, Jogat Gogoi, Kripamoy Aguan, Snehadrinarayan Khatua

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00002A, Paper Bhaskar Sen, Jogat Gogoi, Kripamoy Aguan, Snehadrinarayan Khatua A solvatochromic cyclometalated Ir( III ) complex-based probe containing a click-generated ligand is reported for the highly selective and sensitive light-up luminescent detection of HOCl through C(sp 2 )–H hydroxylation in a mixed aqueous buffer medium. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Urinary metabolomic characterization of meclofenoxate based on UHPLC-Q exactive HF orbitrap MS technology

2026-02-26

Bing Liu, Wennuo Xu, Tingyuan Zheng, Zhongquan Li, Jingjing Zhao

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01344E, Paper Bing Liu, Wennuo Xu, Tingyuan Zheng, Zhongquan Li, Jingjing Zhao This study demonstrated significant intergroup differences in the metabolites of urine samples before and after the administration of meclofenoxate and further screened for eight major potential biomarkers. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

A boron-doped diamond interdigital sensor with an alternating excitation strategy for integrated conductivity and free chlorine measurement

2026-02-25

Yujing Xiao, Xiaopeng Chen, Yunzhe Han, Jiawen Yin, Xin Zhang, Yangbo Wu, Qinghui Jin

Analyst , 2026, Advance Article DOI : 10.1039/D6AN00030D, Paper Yujing Xiao, Xiaopeng Chen, Yunzhe Han, Jiawen Yin, Xin Zhang, Yangbo Wu, Qinghui Jin This study addresses the requirement for precise detection of free chlorine in swimming pool water by proposing and validating an electrochemical sensor based on boron-doped diamond (BDD) electrodes. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

A single fluorescent probe for simultaneous detection of Zn2+, Cd2+, and Pb2+ in industrial wastewater with application in bio-imaging and molecular logic gates

2026-02-25

Chandi Charan Ghosh, Snigdha Roy, Sowmadeep Das, Sanju Das, Ambarish Ray, Partha Pratim Parui

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01239B, Paper Chandi Charan Ghosh, Snigdha Roy, Sowmadeep Das, Sanju Das, Ambarish Ray, Partha Pratim Parui Pb 2+ , which distinguishes the fluorescence of Zn( II )- from Cd( II )-complex, is used to detect Zn 2+ , Cd 2+ , and Pb 2+ in mixtures. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Negative selection assisted isolation of a highly selective DNA aptamer for the detection of 17α-ethinylestradiol

2026-02-25

Nathania Lui, Qiushi Liu, Juewen Liu

Analyst , 2026, Advance Article DOI : 10.1039/D5AN01374G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Nathania Lui, Qiushi Liu, Juewen Liu Using 17α-ethinylestradiol as a target and 17β-estradiol as a counter target, a highly selective aptamer with nanomolar affinity was obtained for 17α-ethinylestradiol, a synthetic estrogenic compound of significant environmental concern. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Development of advanced voltammetric method for telmisartan and study of oxidation mechanism on boron-doped diamond electrode

2026-02-23

Gustavo Fix, Ana Heloísa Fonseca Ayala, Carla Cristina Perez, Elen Romão Sartori

Analyst , 2026, 151 ,1914-1925 DOI : 10.1039/D6AN00034G, Paper Gustavo Fix, Ana Heloísa Fonseca Ayala, Carla Cristina Perez, Elen Romão Sartori A boron-doped diamond electrode was employed to develop a voltammetric method for telmisartan determination. The method was validated and applied in real samples. Electrochemistry coupled with NMR identified the oxidation product. The content of this RSS Feed (c) The Royal Society of Chemistry

Continuous monitoring of glutamate using electroactive templated polymers as synthetic molecular receptors

2026-02-23

Samin Motallebzadeh, Leila Ahmadian-Alam, Masoumeh Bahrami, Arturo Andrade, Edward Song

Analyst , 2026, 151 ,2037-2048 DOI : 10.1039/D5AN01088H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Samin Motallebzadeh, Leila Ahmadian-Alam, Masoumeh Bahrami, Arturo Andrade, Edward Song Electroactive and target-templated polymers can be used as selective bioreceptors for the continuous monitoring of non-electroactive species such as L -glutamate. The content of this RSS Feed (c) The Royal Society of Chemistry

Raman spectroscopic monitoring of multiproduct chemical reaction kinetics; the case of ester hydrolysis

2026-02-23

Muhammed Kashif, Mark E. Keating, Hugh J. Byrne

Analyst , 2026, 151 ,2024-2036 DOI : 10.1039/D5AN01055A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Muhammed Kashif, Mark E. Keating, Hugh J. Byrne Seeded MCR-ALS with optimized seeding weights enhances spectral unmixing by mitigating rank deficiency issues, yielding reliable concentration profiles, reducing residual errors and enhancing kinetic interpretation. The content of this RSS Feed (c) The Royal Society of Chemistry

A portable electrochemical platform for biorecognition-free detection of ochratoxin A and ascorbic acid for food safety and quality monitoring

2026-02-17

Brateen Datta, Raghavv Raghavender Suresh, Gorachand Dutta

Analyst , 2026, 151 ,2067-2076 DOI : 10.1039/D5AN00992H, Paper Brateen Datta, Raghavv Raghavender Suresh, Gorachand Dutta Simultaneous electrochemical detection of ochratoxin-A and ascorbic acid on the TeO 2 –NiO-modified screen-printed paper electrode surface for on-site application. The content of this RSS Feed (c) The Royal Society of Chemistry

Shielded loop-mediated catalytic hairpin assembly for the specific detection of microRNA

2026-02-13

Jiani Wang, Fuxian Ge, Jing Wang, Di Zhang, Miran Tang

Analyst , 2026, 151 ,2060-2066 DOI : 10.1039/D5AN00955C, Paper Jiani Wang, Fuxian Ge, Jing Wang, Di Zhang, Miran Tang MicroRNAs (miRNAs) are highly promising biomarkers, especially in the diagnosis, prognosis and therapeutic monitoring of diseases such as cancer. The content of this RSS Feed (c) The Royal Society of Chemistry

Digital fluorescent pH probes: polymer-based design, fluorescence response, mechanism, functional tuning and application to logic operation in live cells

2026-02-12

Seiichi Uchiyama, Eiko Hamada, Masaharu Takarada, Kohki Okabe

Analyst , 2026, 151 ,1978-1991 DOI : 10.1039/D5AN01187F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Seiichi Uchiyama, Eiko Hamada, Masaharu Takarada, Kohki Okabe We developed polymers that exhibit digital-type fluorescence responses to pH variations in aqueous solution and applied them to intracellular logic operations. The content of this RSS Feed (c) The Royal Society of Chemistry