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8 parsed articles
Last update: 2026-09-21
2026-09-16
Vivien Marx
Prototypes of specially engineered transmission electron microscopes deliver images with greatly improved contrast to cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) projects.
DOI: 10.1038/s41592-026-03239-y2026-09-16
Helena Klara Jambor, Fateme Rajabiyazdi, Verena Prantl, Matthias Flotho, Torsten Möller, Cagatay Turkay
Some visualizations resonate while others are forgotten. Why that is can be understood with the principles of creating ‘proximity’.
DOI: 10.1038/s41592-026-03241-42026-09-14
Tony Chen, Haoyu Zhang, Rahul Mazumder, Xihong Lin
Rather than relying on pre-specified ancestry labels, which often fail to capture the full genetic heterogeneity of diverse populations, SPLENDID treats ancestry as a continuum and improves polygenic risk score (PRS) prediction for biobank-scale datasets.
DOI: 10.1038/s41592-026-03235-22026-09-14
Fatemeh Abbasi, Katharina Rieck, Matthias Brandt, Maja Matis, Eva Kiermaier, Timo Betz
CFM enables tunable cell confinement for measuring traction forces exerted by single cells and cell aggregates in tissue-mimicking microenvironments.
DOI: 10.1038/s41592-026-03216-52026-09-11
Giang N. T. Le, Lam M. T. Pham, Boyan Xue, Maruti Uppalapati, G. Andrew Woolley
A compact protein pair that heterodimerizes upon red light activation, FenixS and Ash1, is developed for optogenetic applications.
DOI: 10.1038/s41592-026-03223-62026-09-10
Studying the brain mechanisms of natural behaviors is experimentally challenging. We developed a miniaturized, wireless platform to record and manipulate neural and physiological activity in small animals, enabling the study of neural mechanisms underlying rodent social group behaviors across laboratory and outdoor natural environments.
DOI: 10.1038/s41592-026-03221-82026-09-10
Zifang Zhao, Hongyu Chang, Praveen Paudel, Jaehyo Park, Can Liu, Maria Q. Aurelio, Azahara Oliva, Antonio Fernandez-Ruiz
WILD is a wireless device that can record neuronal activity, perform optogenetic stimulations, record animal movements, record the environment or eye movements via an integrated camera, analyze the data and trigger optogenetic stimulation. This device facilitates studies of brain activity in freely moving animals such as mice, both in the laboratory and under naturalistic conditions.
DOI: 10.1038/s41592-026-03220-92026-09-08
Vivien Marx
Many have dreamt of studying and getting their scientific training in the United States. These days, that dream is no easy pursuit.
DOI: 10.1038/s41592-026-03240-5