2026-07-27
Binwu Tang
Nature Cell Biology, Published online: 27 July 2026; doi:10.1038/s41556-026-02013-8 Using a dynamic fluorescent reporter, Tang et al. demonstrate that cancer stem cells are hyper-responsive to microenvironmental cues, which they sense and adapt to through YAP/TAZ signalling, thereby playing an essential role in breast cancer lung metastasis.]]>
DOI: 10.1038/s41556-026-02013-82026-07-24
Veronica J. Farmer
Nature Cell Biology, Published online: 24 July 2026; doi:10.1038/s41556-026-02012-9 In this Comment, we call on scientists to share their stories. Through casual conversation or prepared presentations, with images or essays, scientists can advocate for their research and reach taxpayers and elected officials at a time when science funding and public trust are undermined, particularly in the USA.]]>
DOI: 10.1038/s41556-026-02012-92026-07-20
Yuanchun Luo
Nature Cell Biology, Published online: 20 July 2026; doi:10.1038/s41556-026-02010-x Luo et al. describe a budding type of lysosome fission linked to delivery of MFF from mitochondrial-derived vesicles to lysosomes. MFF recruits DRP1 for membrane scission. This axis restores lysosome function during hypoxia–reoxygenation stress.]]>
DOI: 10.1038/s41556-026-02010-x2026-07-13
Petra Gross
Nature Cell Biology, Published online: 13 July 2026; doi:10.1038/s41556-026-02026-3 Cargo capture during ER-phagy]]>
DOI: 10.1038/s41556-026-02026-32026-07-08
Dohun Kim
Nature Cell Biology, Published online: 08 July 2026; doi:10.1038/s41556-026-02004-9 This Review discusses the spatial organization of nucleotide metabolism and its integration with cellular signalling pathways, emphasizing its importance as a dynamic regulatory axis in both physiological contexts and disease.]]>
DOI: 10.1038/s41556-026-02004-92026-06-26
Nature Cell Biology, Published online: 26 June 2026; doi:10.1038/s41556-026-02008-5 The exact routes and mechanisms of iron acquisition by mitochondria are unclear. We identify mitochondria–endoplasmic reticulum contact sites as an iron supply hub and reveal that the mitochondrial ubiquitin ligase MITOL regulates HMOX2 activity, to enable delivery of haem-derived iron to sustain mitochondrial iron homeostasis.]]>
DOI: 10.1038/s41556-026-02008-52026-06-17
Xiaohui Zhang
Nature Cell Biology, Published online: 17 June 2026; doi:10.1038/s41556-026-02001-y Author Correction: Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain]]>
DOI: 10.1038/s41556-026-02001-y2026-06-16
Yanzhu Yue
Nature Cell Biology, Published online: 16 June 2026; doi:10.1038/s41556-026-02011-w Author Correction: Long-term, in toto live imaging of cardiomyocyte behaviour during mouse ventricle chamber formation at single-cell resolution]]>
DOI: 10.1038/s41556-026-02011-w2026-06-15
Zhe Wang
Nature Cell Biology, Published online: 15 June 2026; doi:10.1038/s41556-026-01990-0 Spatial profiling in bladder cancer]]>
DOI: 10.1038/s41556-026-01990-02026-06-15
Guang Peng
Nature Cell Biology, Published online: 15 June 2026; doi:10.1038/s41556-026-01997-7 Author Correction: BRIT1/MCPH1 links chromatin remodelling to DNA damage response]]>
DOI: 10.1038/s41556-026-01997-72026-06-11
Sifan Rong
Nature Cell Biology, Published online: 11 June 2026; doi:10.1038/s41556-026-01993-x This Perspective highlights the use of current proteomics technologies in defining stage-specific reprogramming events to understand reproductive ageing, improve oocyte quality, and refine the outcomes of assisted reproductive technology (ART).]]>
DOI: 10.1038/s41556-026-01993-x2026-03-30
Nature Cell Biology, Published online: 30 March 2026; doi:10.1038/s41556-026-01932-w Paraspeckle condensates are membraneless nuclear organelles linked to stress responses and disease states. We demonstrate that paraspeckle assembly is tightly controlled by antagonism between TDP-43 and other paraspeckle proteins, through non-random distribution of TDP-43 binding sites on the scaffolding RNA NEAT1. Structural changes in NEAT1 or altered protein stoichiometry affect condensate formation, with implications for neurodegeneration.
2026-03-27
Xiaozhou Yu, Xiao Song, Richard A. Schäfer, Qingshu Meng, Deanna Tiek, Runxin Wu, Qiu He, Maya Walker, Qi Cao, Rendong Yang, Bo Hu, Shi-Yuan Cheng
Nature Cell Biology, Published online: 27 March 2026; doi:10.1038/s41556-026-01924-w Yu et al. identify HELDR as a lncRNA co-amplified with EGFR in glioblastoma to promote a KAT7-activated malignancy programme, which can be potentially targeted with anti-EGFR therapy for improved therapeutic outcomes.
2026-03-20
Aubrey Weigel
Nature Cell Biology, Published online: 20 March 2026; doi:10.1038/s41556-026-01919-7 A study establishes a correlative light and electron microscopy workflow that reveals how individual lipid species distribute across nanoscale membrane domains, uncovering sphingomyelin sorting within the early endosome.