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npj Systems Biology and Applications

Publisher:
Springer Nature
ISSN:
2056-7189
Category:
MATHEMATICAL & COMPUTATIONAL BIOLOGY
Impact factor:
3.5

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6 parsed articles

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Latest articles

Unifying theories in high-dimensional biophysics: approaches, challenges and opportunities

2026-03-28

Marianne Bauer, Akshit Goyal, Sidhartha Goyal, Gautam Reddy, Shaon Chakrabarti, Michael M. Desai, William Gilpin, Jacopo Grilli, Kabir Husain, Sanjay Jain, Mohit Kumar Jolly, Kyogo Kawaguchi, Aneta Koseska, Milo Lin, Leelavati Narlikar, Simone Pigolotti, Archishman Raju, Krishna Shrinivas, Rahul Siddharthan, Greg J. Stephens, Andreas Tiffeau-Mayer, Suriyanarayanan Vaikuntanathan

npj Systems Biology and Applications, Published online: 28 March 2026; doi:10.1038/s41540-026-00680-9 Across biological subdisciplines, the last decade has seen an explosion of high-dimensional datasets. At the ICTS workshop ‘Unifying Theories in High-Dimensional Biophysics’, we discussed whether this high dimensionality poses a challenge or an opportunity for theoretically describing, understanding and predicting biological systems. We discussed methods, models and frameworks that can be used for this purpose. This Comment summarizes our discussions from the perspectives of individual participants.

From FAIR to CURE: guidelines for computational models of biological systems

2026-03-27

Herbert M. Sauro, Eran Agmon, Michael L. Blinov, John H. Gennari, Joseph L. Hellerstein, Adel Heydarabadipour, Bartholomew E. Jardine, Elebeoba May, David P. Nickerson, Lucian P. Smith, Gary D. Bader, Frank T. Bergmann, Patrick M. Boyle, Andreas Dräger, James R. Faeder, Song Feng, Juliana Freire, Fabian Fröhlich, James A. Glazier, Thomas E. Gorochowski, Tomas Helikar, Henning Hermjakob, Stefan Hoops, Peter Hunter, Princess I. Imoukhuede, Sarah M. Keating, Matthias König, Reinhard Laubenbacher, Leslie M. Loew, Carlos F. Lopez, William W. Lytton, Rahuman S. Malik-Sheriff, Andrew McCulloch, Pedro Mendes, Lealem Mulugeta, Chris J. Myers, Jerry G. Myers Jr, Anna Niarakis, David D. van Niekerk, Brett G. Olivier, Alexander A. Patrie, Ellen M. Quardokus, Nicole Radde, Johann M. Rohwer, Sven Sahle, James C. Schaff, Falk Schreiber, T. J. Sego, Janis Shin, Jacky L. Snoep, Rajanikanth Vadigepalli, H. Steven Wiley, Dagmar Waltemath, Ion I. Moraru

npj Systems Biology and Applications, Published online: 27 March 2026; doi:10.1038/s41540-026-00651-0 From FAIR to CURE: guidelines for computational models of biological systems