Nature Reviews Nephrology

Publisher:: Springer Nature
ISSN:: 1759-5061
Category:: UROLOGY & NEPHROLOGY
Impact factor:: 28.6

Official website ↗Official RSS source ↗

Feed status

3 parsed articles

Last update: Not fetched

Latest articles

Future needs for clinical trials in autosomal dominant polycystic kidney disease

2026-03-24

Karla M. Márquez-Nogueras, Ivana Y. Kuo, Arlene B. Chapman

Nature Reviews Nephrology, Published online: 24 March 2026; doi:10.1038/s41581-026-01070-4 Autosomal dominant polycystic kidney disease is the most common inherited cause of kidney failure, yet therapeutic interventions remain limited. Scientific advances are undoubtedly catalysing the development of new interventions; however, consideration of randomized clinical trials that have been conducted to date provide important insights that should guide the development of future trials.

The endothelium response to kidney injury

2026-03-23

Kyle H. Moore, Arin L. Melkonian, James F. George, Anupam Agarwal

Nature Reviews Nephrology, Published online: 23 March 2026; doi:10.1038/s41581-026-01067-z The kidney contains a heterogeneous endothelial cell population that serve distinct roles in the maintenance of tissue homeostasis and kidney function. This Review summarizes current understanding of the endothelial response to kidney injury, focusing on the response of vascular, glomerular and lymphatic endothelial cells in diverse kidney diseases, and describes the potential of emerging endothelium-targeted therapeutics to ameliorate injury and restore kidney function.

A path to reduce chronic kidney disease burden in Samoa

2026-03-17

Malama Tafuna’i, Robert Walker

Nature Reviews Nephrology, Published online: 17 March 2026; doi:10.1038/s41581-026-01068-y Early detection, strong primary care and community-based active conservative kidney management must form the foundation of Samoa’s response to chronic kidney disease (CKD). With diabetes driving the majority of CKD and kidney failure cases, prevention and primary care investment must be prioritized to enable the later expansion of nephrology services.