Cell Discovery

FAM50A promotes esophageal squamous cell carcinoma progression via splicing-dependent oncogenic circSDK1- and DUSP22-mediated MAPK/FAK activation

2026-10-20

Yan Bian, Ye Gao, Xin Chang, Bo Tian, Qianqian Meng, Lei Xin, Han Lin, Wei Wang, Zhaoshen Li, Luowei Wang

Structural insights into the ligand modulation of MRGPRX4 conformational plasticity

2026-10-13

Mengna Zhang, Yongxia Wang, Yun Huang, Yaqi Liang, Pengxiao Chen, Zheng Ji, Minghu Song, He Chen, Chunyu Wang, Can Cao

Author Correction: A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration

2026-10-13

Yunyun Jin, Qianqian Liu, Peng Chen, Siyuan Zhao, Wenhao Jiang, Fanhua Wang, Peng Li, Yuanjin Zhang, Weiqiang Lu, Tao P. Zhong, Xinran Ma, Xin Wang, Alison Gartland, Ning Wang, Karan Mehul Shah, Hankun Zhang, Xu Cao, Lei Yang, Mingyao Liu, Jian Luo

Author Correction: Breast cancer induces CD62L + Kupffer cells via DMBT1 to promote neutrophil extracellular trap formation and liver metastasis

2026-10-13

Pu Tian, Qiuyao Wu, Dasa He, Wenjing Zhao, Lichao Luo, Zhenchang Jia, Wenqian Luo, Xianzhe Lv, Yanan Liu, Yuan Wang, Qian Wang, Peiyuan Zhang, Yajun Liang, Qifeng Yang, Guohong Hu

Blocking PD1 prevents T-cell-promoted fibrosis in myocardial infarction

2026-10-06

Xiaoying Chen, Changchen Xiao, Changle Ke, Jiamin Li, Ye Liu, Junhua He, Mo Li, Jing Zhao, Zhiwei Zhong, Qiming Chen, Tingting Hong, Fei Liao, Feimu Zhang, Yu Zhang, Jiayue Cai, Shuyuan Sheng, Qingju Li, Yongjian Chen, Yinghui Xu, Jingyi Wang, Shuhan Zhong, Xianpeng Wu, Peng Shi, Yang Xu, Wei Zhu, Xinyang Hu, Cheng Ni, Jian’an Wang

Structural basis of the transport mechanism of hBGT1

2026-09-29

Kun Hao, Jiahui Chen, Jun Zhao, Renjie Li, Yue Li, Pu Yuan, Qinru Bai, Yanli Dong, Jie Yu, Yan Zhao

Eggerthella lenta disrupts the gut vascular barrier to drive colorectal cancer liver metastasis

2026-09-22

Cheng Kong, Yutao Jin, Guang Liu, Yangyang Guo, Fanying Guo, Yanlei Ma

The accessory protein ORF3a hijacks the CLCC1 chloride channel to disrupt ER homeostasis in betacoronavirus pathogenesis

2026-09-15

Liang Guo, Baoying Huang, Hanzhi Yu, Yi Xu, Lei Wei, Jijie Zheng, Yuanzhe Li, Di Wu, Peng Zhao, Changcheng Wu, Wenjie Tan, Yichang Jia

Structural basis of human zinc-activated channel (ZAC) signaling and modulation

2026-03-31

Zixuan Zhou, Yonghui Long, Yulin Chao, Chuanhui Yang, Yi-Quan Tang, Yilai Shu, Hongtao Zhu, Anders A. Jensen, Qianhui Qu

Cell Discovery, Published online: 31 March 2026; doi:10.1038/s41421-026-00878-5 Structural basis of human zinc-activated channel (ZAC) signaling and modulation

Highly regional generation and heterogeneous differentiation of basal cells in mouse trachea

2026-03-30

Xiuxiu Liu, Wendong Weng, Zhen He, Kuo Liu, Maoying Han, Wenjuan Pu, Bin Zhou

Cell Discovery, Published online: 30 March 2026; doi:10.1038/s41421-026-00887-4 Highly regional generation and heterogeneous differentiation of basal cells in mouse trachea