BRAIN BEHAVIOR AND IMMUNITY

Steven F. Maier: a life of scientific discovery, intellectual curiosity, and lasting influence

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Monika Fleshner, Michael V. Baratta, Jerry W. Rudy

Hope is linked with more favorable tumor molecular signatures in serous ovarian cancer

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Susan K. Lutgendorf, Benjamin W. Corn, Premal H. Thaker, Michael J. Goodheart, Frank J. Penedo, Anil K. Sood, Steven W. Cole

Astrocytes reduce microglial activation and enhance adult hippocampal neurogenesis in acute inflammation

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Publication date: Available online 19 May 2026 Source: Brain, Behavior, and Immunity Author(s): Marta Vilademunt, Irmak Çabas, Fabio Grieco, Charline Carron, Thibault Sprenger, Thomas Larrieu, Jean-René Cardinaux, Nicolas Toni

Corrigendum to “Complement activation sustains neuroinflammation and deteriorates adult neurogenesis and spatial memory impairment in rat hippocampus following sleep deprivation” [Brain Behav. Immun. 82 (2019) 129–144]

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Publication date: October 2026 Source: Brain, Behavior, and Immunity, Volume 137 Author(s): Meetu Wadhwa, Amit Prabhakar, Jag Pravesh Anand, Koushik Ray, Dipti Prasad, Bhuvnesh Kumar, Usha Panjwani

Hippocampal C5a-C5aR1 axis drives age-related memory decline via collapsing synaptic chloride homeostasis

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Publication date: November 2026 Source: Brain, Behavior, and Immunity, Volume 138 Author(s): Wenying Liu, Wei Qin, Ying Li, Jianping Jia

DREADDs-Gi mediated inhibition of myeloid cells leads to anti-inflammatory signalling, shrinkage of microglia and acute heart failure in Cx3cr1Cre mice

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Frederik Holde, Tina Myhre Pedersen, Sofie Let Frandsen, Bjarke Thomsen, Vladimir Matchkov, Anna Mathia Klawonn

The association of herpes simplex virus, epstein-barr virus, and cytomegalovirus infections with multiple sclerosis: a large-scale case-control study

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Johnatan Nissan, Uriel Fennig, Yair Tsikinovsky, Karin Melcer, Nicola Maggio, Shlomo Vinker, Roni Loebenstein

Gut microbiota dysbiosis-induced neuroinflammation and IL-22/STAT3 activation in emotional disorders

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Xiangru Feng, Yan Hu, Liangliang Zhu, Xiaoxuan Lu, Lulu Sun, Jiayu Liu, Jiayang Jin, Xiaoguo Ji, Liming Zhao

Is inadequate immune activation in late pregnancy a sign of mental health vulnerability?

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Emma Fransson

Publication date: Available online 14 July 2026 Source: Brain, Behavior, and Immunity Author(s): Emma Fransson

Doxorubicin administration modulates cancer-related fatigue in a time-of-day-dependent manner

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Anneke Kastelein, Ilse R. Kelters, Amy Chin On, Han Jiao, Sonia Martinez Arenas, Rico J.E. Derks, Elena Sánchez-López, Anke M. Smits, Francesco Angeli, Marco Guglielmo, Joost P.G. Sluijter, Martin Giera, Chun-Xia Yi, Jacques Neefjes, Vasco Sampaio-Pinto, Laura Kervezee, Linda W. van Laake, Johanna H. Meijer

Astrocyte reactivity by alcohol dependence in the central amygdala

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Publication date: October 2026 Source: Brain, Behavior, and Immunity, Volume 137 Author(s): Joel G. Hashimoto, Angela E. Gonzalez, Natalie Gorham, Zoe Barbour, Amanda J. Roberts, Le Z. Day, Hermina Nedelescu, Maci Heal, Brett A. Davis, Lucia Carbone, Jon Jacobs, Marisa Roberto, Marina Guizzetti

Perceived everyday discrimination and leukocyte gene expression in a nationally representative sample of U.S. Adults

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Alisha A. Crump, Xiaoyan Zhang, Jemar R. Bather, Mariana Rodrigues, Emiko O. Kranz, Steve W. Cole, Kathleen M. Harris, Adolfo G. Cuevas

Perceived everyday discrimination and leukocyte gene expression in a nationally representative sample of U.S. Adults

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Alisha A. Crump, Xiaoyan Zhang, Jemar R. Bather, Mariana Rodrigues, Emiko O. Kranz, Steve W. Cole, Kathleen M. Harris, Adolfo G. Cuevas

Serum neurofilament light chain increases in healthy postpartum: is it subclinical brain damage or neuroplasticity?

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Publication date: October 2026 Source: Brain, Behavior, and Immunity, Volume 137 Author(s): Antonio Bertolotto, Paola Valentino, Cecilia Irene Bava, Serena Martire, Simona Malucchi, Lucia Giorgi, Carola Beltratti, Alessia Di Sapio, Luca Marozio

Combined low-dose (2R,6R)-Hydroxynorketamine and memantine restore BDNF/TrkB signaling and synaptic function in an LPS-induced model of depressive-like behavior in male mice

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Xiaoli Jia, Qichao Gong, Bocheng Xiong, Yue Hu, Tahir Ali, Chengyou Zheng, Shoupeng Wei, Jianxiang Huang, Zhangting Wang, Jinxing Feng, Shupeng Li

Omega-3 supplementation reduces perceived social isolation in a sex-dependent manner: Secondary analysis of an RCT

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Annelise A. Madison, Tatum A. Jolink, Stephanie J. Wilson, M. Rosie Shrout, Martha A. Belury, William B. Malarkey, Janice K. Kiecolt-Glaser

Publication date: Available online 6 July 2026 Source: Brain, Behavior, and Immunity Author(s): Annelise A. Madison, Tatum A. Jolink, Stephanie J. Wilson, Rosie Shrout, Martha A. Belury, William B. Malarkey, Janice K. Kiecolt-Glaser

Bone marrow remodeling and brain–bone marrow crosstalk in Alzheimer’s disease-like neurodegeneration

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Konstantin Yenkoyan, Tigran Davtyan, Hamlet Torosyan, Sona Galstian, Vergine Chavushyan

From neuroinflammation to synaptic rewiring: HMGB1 as a central integrator in methamphetamine addiction

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Fangmin Wang, Huizhen Liu, Chaoyang Chu, Wenhua Zhou

Positive childhood experiences and associations with plasma inflammatory markers in early adulthood

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Publication date: October 2026 Source: Brain, Behavior, and Immunity, Volume 137 Author(s): Jennifer Murphy, Joshua Gilheany, David Mongan, Colm Healy, Mary Cannon, David R. Cotter

Response to the Letter to the Editor regarding our article “Role of AQP4-mediated glymphatic system dysfunction in postoperative neuroinflammation and cognitive dysfunction”

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Han Zhou, Bo Lu

Publication date: Available online 11 July 2026 Source: Brain, Behavior, and Immunity Author(s): Han Zhou, Bo Lu

The association of herpes simplex virus, epstein-barr virus, and cytomegalovirus infections with multiple sclerosis: a large-scale case-control study

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Johnatan Nissan, Uriel Fennig, Yair Tsikinovsky, Karin Melcer, Nicola Maggio, Shlomo Vinker, Roni Loebenstein

Brain-derived extracellular vesicle (BDEV) abundance and BDEV protein associations with clinical phenotypes and treatment response in untreated first-episode psychosis

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Publication date: Available online 12 July 2026 Source: Brain, Behavior, and Immunity Author(s): Lusi Zhang, Adam M. Lee, Zia L. Maxim, Manjula Munirathinam, Bart S. Larsen, Michael K. Georgieff, Sarah K. Keedy, James L. Reilly, John A. Sweeney, Phu V. Tran, Jeffrey R. Bishop

Therapeutic potential of a novel PPARγ agonist in a mouse model of HIV-associated neurocognitive impairment

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Celene Titus, Md. Tozammel Hoque, Robert Bonin, Reina Bendayan

Disrupting peripheral serotonin synthesis drives sex-specific alterations in sociability and cognition, and reshapes the gut-immune-brain axis

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Rogério C.R. Castro, Natalia Alenina, Eugenia E. Natasha, Thijs Lodder, Aiswarya R. Nair, Susanne C. Gonçalves, Lingling Mai, Danique Mulder, Rob Woestenenk, Rick Hesen, Marta C.F. Samina, Tianhua Wang, Markus Wöhr, Sharon M. Kolk, Michael Bader, Alejandro A. Vasquez, Jan K. Buitelaar, Michel M.M. Verheij, Judith R. Homberg

Association between inflammatory biomarkers and depressive symptoms in breast cancer: a systematic review

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Publication date: August 2026 Source: Brain, Behavior, and Immunity, Volume 136 Author(s): Kareena Patel, Sophia N. Karagiannis, Alessandra Borsini

Early life stress in mice disrupts blood–brain barrier function and reduces claudin-5 expression in the lateral septum and striatum, with linked behavioral impairments

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Beyond the cranium: How the bone marrow regulates the ischemic brain

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Publication date: August 2026 Source: Brain, Behavior, and Immunity, Volume 136 Author(s): Wook-Jin Chae, Theingi Aung, Charita Valipireddy

Impact of voluntary exercise on obesity-induced brain pathology: Insights from a multimodal approach in male Ldlr-/-.Leiden mice

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Probiotic treatment rescues behavioral deficits and gut microbial abnormalities induced by preconceptional stress in mothers and offspring

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Sexually dimorphic roles of toll-like receptors in the central nervous system

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Publication date: October 2026 Source: Brain, Behavior, and Immunity, Volume 137 Author(s): Stella Elkabes